Lipoprotein(a)-associated atherogenesis may increase Coronary Heart Disease Risk: Study
Written By : Jacinthlyn Sylvia
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2024-03-19 16:30 GMT | Update On 2024-03-19 16:30 GMT
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In a recent genetic analysis published in the Journal of the American College of Cardiology uncovered a compelling evidence that lipoprotein(a) (Lp(a)), a risk factor for coronary heart disease (CHD), holds a significant atherogenicity that is six times greater than low-density lipoprotein (LDL) on a per-particle basis.
After utilizing the genome-wide association studies within the UK Biobank population Elias Björnson and team identified two clusters of single nucleotide polymorphisms related to Lp(a) and LDL concentrations. Both Lp(a) and LDL were found to contain one apolipoprotein B (apoB) per particle which formed the basis for a comparative analysis.
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