Multiple arterial grafting in CABG reduce long-term mortality in diabetes patients

UK: In a new study published in the European Heart Journal, it was shown that compared to single arterial grafting (SAG), multiple arterial grafting (MAG) relatively reduced mortality and major adverse cardiac events (MACE) rates after coronary artery bypass grafting (CABG) up to 10 years. 

Despite significant breakthroughs in medical care, coronary artery disease (CAD) has long been recognized as a major source of morbidity and death in people with diabetes mellitus (DM). In individuals with diabetes and multi-vessel coronary disease, CABG has proven to be a better approach of revascularization when compared to percutaneous coronary intervention. As a result, David P. Taggart and colleagues conducted a post-hoc examination of the influence of MAG on CABG outcomes based on diabetes status in the Arterial Revascularization Trial (ART).

At a 10-year follow-up, the primary objective was all-cause death, and the secondary endpoint was a composite of major adverse cardiac events (MACE). Patients were divided into two groups based on their diabetes condition (non-DM and DM) and grafting method (MAG vs. SAG). The study comprised 3020 participants, with 716 (23.7%) having diabetes. In all, 55.8% of non-DM patients were given MAG and 44.2% were given SAG, whereas 56.6% of DM patients were given MAG and 43.4% were given SAG.