Patients with electrical storm and reduced LVEF best suited for early Catheter ablation strategy compared to medical therapy: Study
Researchers have demonstrated that catheter ablation (CA) significantly improves survival in patients with electrical storm (ES), particularly those with a reduced left ventricular ejection fraction (LVEF). ES is a life-threatening condition defined by recurrent ventricular arrhythmias with high early and subacute mortality rates. Even though CA is an established treatment option, the effect of the procedure on short-term and midterm survival has been unclear. A recent study was conducted by Karim B. and colleagues which was published in the journal of JACC: Clinical Electrophysiology.
The study involved 780 consecutive patients admitted with ES across four tertiary centers. The differences in baseline characteristics between the treatment groups were accounted for by propensity score matching. After matching, 288 patients underwent CA, and 288 received medical therapy alone. The demographic characteristics, ES presentation, and management strategies were comparable between the groups, thus ensuring balanced comparisons.
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