Ticagrelor ups death and bleeding risk in elderly MI patients: SWEDEHEART Registry
Stockholm, Sweden: The use of ticagrelor versus clopidogrel in elderly myocardial infarction (MI) patients increases the risk of death and bleeding, suggests a recent study in the journal Circulation.
To determine comparative efficacy and safety of ticagrelor vs. clopidogrel in older MI patients Karolina Szummer, Karolinska University Hospital, Stockholm, Sweden, and colleagues performed an observational analysis of all patients ≥80 years (n = 14,005) who were discharged alive with aspirin combined with either clopidogrel (60.2%) or ticagrelor (39.8%) after MI. The patients were registered in the national registry SWEDEHEART (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) between 2010 and 2017.
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