Changing Face of Cancer Treatment: 3 scientists share USD 500,000 prize for Development of Immunotherapy techniques

"Their impact on the development of cancer immunotherapy - and where it goes from here - is unsurpassed."

Immunotherapy harnesses the power of the immune system to attack cancer cells and tumours.

In the 1980s, Rosenberg theorized that stimulating white blood cells called T cells could provoke immune reactions.

His work led to the first immunotherapy drug approved by the US Food and Drug Administration to treat cancer in 1992.

Former President Jimmy Carter credited the new immune therapy drug Keytruda with shrinking his brain tumours in 2015.

The drug, developed using an approach pioneered by Allison, is among a new class of genetically engineered antibody-based medicines that are transforming treatment for several kinds of cancer with drugs that are often less toxic than chemotherapy.

June has led groundbreaking work in developing CAR-T cell therapies, which alter a patient's own blood cells to turn them into specialized cancer killers.

CAR-T therapy became the first `FDA-approved personalized cellular therapy for cancer in 2017 with the approval of Kymriah to treat certain pediatric and young adult leukaemia patients.