APAP-MAD therapy combo significantly decreased daytime sleepiness among sleep apnea patients

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2022-12-18 14:30 GMT | Update On 2022-12-19 07:18 GMT

APAP-MAD therapy combo significantly increased compliance with APAP therapy among patients with moderate-to-severe OSA suggests a recent study published in the European Journal of Dentistry.

The purpose of this pilot study was to determine whether compliance to auto-adjusting positive airway pressure (APAP) improves with the addition of a mandibular advancement device (MAD). Secondary outcome measures included were APAP pressure, subjective daytime sleepiness, apnea–hypopnea index (AHI), and mask leaks.

Participants included were diagnosed with moderate-to-severe obstructive sleep apnea (OSA) and became noncompliant to prescribed APAP. Thirteen participants with a mean age of 61.6 years were recruited for this study. All participants were given a MAD to use with their APAP. Parameters measured included APAP pressure, AHI, mask leak reported via ResMed AirViewTM software, and self-reported daytime sleepiness (Epworth Sleepiness Scale [ESS]). A paired two-sample for mean t-test was performed to determine significance.

Results:

• The mean difference of pre- and postintervention APAP compliance was 23.1%, which was statistically significant (p = 0.015).

• The mean APAP air pressures were unchanged.

• The difference between pre- and postintervention mean ESS scores was 1.4 and was statistically significant (p = 0.027).

• The mean difference between pre- and postintervention AHI values and mask leak showed no significant difference.

This study showed that combination of APAP-MAD therapy, for patients with moderate-to-severe OSA who were noncompliant to APAP use, significantly increased compliance with APAP therapy, and significantly decreased the daytime sleepiness of participants.

Reference:

Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington. Continuous Positive Airway Pressure-Mandibular Advancement Device Combination Therapy for Moderate-to-Severe Obstructive Sleep Apnea: A Preliminary Study. CC BY 4.0 · Eur J Dent 2022; 16(04): 749-755. DOI: 10.1055/s-0040-1719220

Keywords:

APAP-MAD, therapy, combo ,significantly, increased, compliance, APAP, therapy, patients moderate-to-severe OSA, Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington

Article Source : European Journal of Dentistry

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Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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APAP-MAD therapy combo significantly decreased daytime sleepiness among sleep apnea patients

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