Gingival Capillary BFV Identified as Early Inflammation Marker in gingival sulcus: Study

Published On 2025-08-18 15:15 GMT   |   Update On 2025-08-18 15:15 GMT
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A recent study has identified gingival capillary blood flow velocity (BFV) as a promising noninvasive marker for early detection of inflammation in the gingival sulcus, offering a potential breakthrough in periodontal diagnostics. Researchers measured BFV using advanced imaging techniques and observed that changes in flow velocity closely corresponded with localized inflammatory activity, even before visible clinical signs emerged. This makes BFV a sensitive and quantifiable parameter for monitoring the earliest stages of gingival inflammation, which is critical for preventing progression to more severe periodontal disease. The study demonstrated that BFV increased significantly in areas showing early inflammatory changes, reflecting local microvascular alterations driven by immune activity. This vascular responsiveness could be leveraged for early screening and real-time monitoring of gingival health, particularly in high-risk patients. The noninvasive nature of BFV measurement makes it suitable for routine dental assessments, especially when traditional signs like swelling or bleeding are not yet apparent. Moreover, the ability to detect inflammation at a microvascular level opens new avenues for evaluating the efficacy of preventive therapies or oral hygiene interventions. By shifting the diagnostic focus from reactive to proactive care, this technique could help improve patient outcomes and reduce the burden of chronic periodontal disease. The study supports the integration of gingival BFV monitoring into standard diagnostic protocols and calls for larger-scale clinical validation across diverse patient populations to confirm its utility in general dental practice.

Reference:
Watanabe, T., Fujita, K., Hirayama, H., & Takahashi, M. (2025). Gingival capillary blood flow velocity as an early marker for inflammation in the gingival sulcus. Archives of Oral Biology. https://doi.org/10.1016/j.archoralbio.2024.105816

Keywords: gingival sulcus, blood flow velocity, inflammation marker, periodontal health, early diagnosis, microcirculation, noninvasive assessment


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Article Source : Cureus

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