Maintenance of oral health linked to reduction of risk of infective endocarditis

This article reviews and analyzes the recently updated guidelines for the prevention of infective endocarditis (IE) through antibiotic prophylaxis established by the American Heart Association (AHA). Various articles studying methods of preventing infective endocarditis were reviewed, primarily the AHA's revised guidelines published in April 2007. Lists of reference articles were examined to cross reference relevant information regarding antibiotic prophylaxis for the prevention of infective endocarditis.

A major influence for revisions to the guidelines is that studies show a very small fraction of infective endocarditis cases are preventable with prophylaxis with antibiotic therapy prior to dental procedures. Infective endocarditis is more likely to result from daily activities, such as brushing and flossing teeth, than from bacteremia caused by dental procedures. Patients with underlying cardiac conditions, who are associated with the most detrimental outcome if infective endocarditis develops, should receive prophylaxis prior to dental procedures.

Thus, maintenance of oral health is more effective in reducing the risk of infective endocarditis than prophylactic antibiotics for dental procedures. An increased lifetime risk of developing infective endocarditis alone is not a basis for prophylaxis, especially considering that adverse events stemming from antibiotic use exceed the benefit of antibiotic prophylaxis.

Reference:

F. Farbod, H. Kanaan, J. Farbod. Infective endocarditis and antibiotic prophylaxis prior to dental/oral procedures: latest revision to the guidelines by the American Heart Association published April 2007. International Journal of Oral and Maxillofacial Surgery, Volume 38, Issue 6,2009, Pages 626-631, ISSN 0901-5027. https://doi.org/10.1016/j.ijom.2009.03.717.

Keywords:

infective endocarditis, antibiotic prophylaxis, dental, oral, revision, guidelines, american heart association, International Journal of Oral and Maxillofacial Surgery, F. Farbod H, Kanaan J. Farbod