Nonsurgical mechanical debridement with adjunctive ozone gels and chlorhexidine effective in periodontal treatment

Periodontal disease is one of the most prevalent diseases, with 1.1 billion prevalent cases worldwide and the 40–49 age group being the most affected. The major etiological factor is the dental biofilm, a structured organization of microorganisms attached to dental hard tissues and immersed in the extracellular matrix. Smoking and diabetes are recognized risk factors, while occlusal trauma, open interproximal contacts, overhanging/over contoured restorations, mucogingival deformities, and anatomical variations are considered contributing factors. A study was done to evaluate the efficacy of newly introduced ozonated gels compared with conventional chlorhexidine gel in the home management of periodontal patients. 30 patients with bilateral periodontal disease (severity I, complexity II) were enrolled (split-mouth study design). After non-surgical mechanical periodontal debridement, the teeth were randomly divided into two groups: teeth in the Control group were treated with a chlorhexidine-based gel to aid oral hygiene manoeuvres for 2 weeks after the first visit, while teeth in the Test group were treated in the same way with ozone-based gels. After the baseline assessment, the follow-up included assessments at 1, 2, and 6 months. The variables evaluated were clinical attachment loss (CAL), probing pocket depth (PPD), bleeding on probing (BoP), plaque control record (PCR), recession (R), and tooth mobility (TM). Results: For clinical attachment loss, probing pocket depth, BoP, and PCR, significant intragroup differences were found for both groups (p < 0.05), in contrast to intergroup differences (p > 0.05). No significant differences were found for R and TM. Nonsurgical mechanical periodontal debridement with adjunctive use of ozone and chlorhexidine was found to be effective in periodontal treatment. Ozone could be suggested as an alternative to chlorhexidine.

Reference:

Scribante, A., Gallo, S., Pascadopoli, M., Frani, M., & Butera, A. (2023). Ozonized gels vs chlorhexidine in non-surgical periodontal treatment: A randomized clinical trial. Oral Diseases, 00, 1–8. https://doi.org/10.1111/odi.14829

Keywords:

Nonsurgical mechanical debridement, ozone gels, chlorhexidine periodontal treatment, Scribante, A., Gallo, S., Pascadopoli, M., Frani, M., & Butera, A