Patients of autoimmune diseases at high risk of developing apical periodontitis

The prevalence of AP was 89.9% in AD patients and 74.2% in control subjects

The DMFT score was found to be significantly higher in the AD group

Patients with RA had the highest risk of being affected by AP, whereas those with IBD had the lowest risk. Multiple binary logistic regression analysis indicated that the teeth of AD patients who were not taking any medication or were being treated with biologic disease-modifying anti-rheumatic drugs (bDMARDs) had a higher risk of being affected by AP than did the teeth of the control subjects

The teeth of patients taking conventional DMARDs (cDMARDs) were less affected by AP compared with those of patients taking bDMARDs.

Patients with AD, whether treated or not with biologic medications, showed a higher prevalence of AP than did those in the control group. The DMFT index score, which was higher in AD patients compared with controls was identified as a significant predictor of AP prevalence.

Reference:

Allihaibi, M., Niazi, S.A., Farzadi, S., Austin, R., Ideo, F., Cotti, E. et al. (2023) Prevalence of apical periodontitis in patients with autoimmune diseases: A case-control study. International Endodontic Journal, 00, 1– 11. Available from: https://doi.org/10.1111/iej.13902

Keywords:

International Endodontic Journal, Patients, autoimmune, diseases, high risk, developing, apical periodontitis, Allihaibi, M., Niazi, S.A., Farzadi, S., Austin, R., Ideo, F., Cotti, E.