Persisting oral infection linked to posttransplant infectious complications, suggests study
Persisting oral infection linked to posttransplant infectious complications, suggests study published in the Journal of Evidence-Based Dental Practice.
Posttransplant infections may lead to dire consequences in immunocompromised organ recipients. Oral foci of infection are therefore often eliminated prior to solid organ transplantation to reduce posttransplant morbidity. However, despite increasing numbers of organ transplantations the necessity of pretransplant dental treatment and its effect on transplant outcome remains uncertain.
The present systematic review aimed to evaluate the impact of oral foci of infection and pretransplant dental treatment on adverse events following solid organ transplantation. Studies on adult patients undergoing solid organ transplantation with/without oral infection or with/without pretransplant dental treatment were eligible. An electronic search in PubMed, Scopus, Web of Science, CINAHL and Cochrane was conducted up to June 11, 2024. Screening of eligibility, data extraction and risk-of-bias assessment of the included studies with the Newcastle-Ottawa Scale were done independently by two reviewers. Data were synthesized with a narrative approach.
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