Probiotic intake deterrent to plaque accumulation: Study

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-03-23 03:30 GMT   |   Update On 2022-03-23 03:30 GMT
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Probiotics are live micro-organisms that when administered in adequate amounts confer health benefits upon the host. The impact of probiotics on oral health is relatively new with lots of research going on; the area of probiotics and periodontal disease is still in its infancy.

Researchers at Moscow have found in a new study that probiotics have positive effect on accumulation of plaque. Further Probiotic intake (Streptococcus salivarius K12) does not affect salivation rates and secretory immunoglobulin, according to a recent study published in the Nutrients.

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Researchers aimed to assess the effect of oral probiotics containing the Streptococcus salivarius K12 strain on the salivary level of secretory immunoglobulin A, salivation rate, and oral biofilm.

Thirty-one consenting patients meeting the inclusion criteria were recruited in this double-blind, placebo-controlled, two-arm, parallel-group study and randomly divided into probiotic (n = 15) and placebo (n = 16) groups.

Unstimulated salivation rate, concentration of salivary secretory immunoglobulin A, Turesky index, and Papillary-Marginal-Attached index were assessed after 4 weeks of intervention and 2 weeks of washout. Thirty patients completed the entire study protocol.

The results of the study are:

They found no increase in salivary secretory immunoglobulin A levels and salivary flow rates in the probiotic group compared with placebo. Baseline and outcome salivary secretory immunoglobulin A concentrations (mg/L) were 226 ± 130 and 200 ± 113 for the probiotic group and 205 ± 92 and 191 ± 97 for the placebo group, respectively. A significant decrease in plaque accumulation was observed in the probiotic group at 4 and 6 weeks. Within the limitations of the present study, it may be concluded that probiotic intake (Streptococcus salivarius K12) does not affect salivation rates and secretory immunoglobulin

Thus, researchers concluded that a salivary levels but exhibits a positive effect on plaque accumulation. 

Reference:

The Effect of Oral Probiotics (Streptococcus Salivarius k12) on the Salivary Level of Secretory Immunoglobulin A, Salivation Rate, and Oral Biofilm: A Pilot Randomized Clinical Trial by Ksenia Babina et al. published in the Nutrients.

https://pubmed.ncbi.nlm.nih.gov/35268099/

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Article Source : Nutrients

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