Resin infiltration effective for maintaining structural integrity of MIH-affected teeth

The authors included a total of fifty-one children aged 6–12 years with at least one incisor and one first permanent molar with yellow/brown MIH opacities. Patients were randomly allocated into three groups: FV – Fluoride Varnish (Duraphat); FV+etch – Fluoride Varnish (Duraphat) after enamel etching with 37% phosphoric acid; or RI – Resin Infiltration system (Icon). Opacities were monitored for 18 months.

The primary outcome was the loss of integrity due to post-eruptive enamel breakdown (PEB). Covariables included sex, age, DMFT index, opacity color, plaque index, number of MIH-affected teeth, and number of MIH-affected surfaces. Fisher's Exact was used to test the association of treatments with PEB, the Kaplan-Meyer method analyzed the survival rates and Cox-regression determined which covariables would predict failure (α=0.05).

The results showed that from a total of 235 teeth, the PEB rate for RI (6.1%) was significantly lower (p<0.05) than FV (17.9%; OR 3.0, 95%CI 1.07, 8.48) and FV+etch (17.3%; OR 3.1, 95%CI 1.13, 8.73) and the DMFT index >3, brown opacities, cusp involvement, and age between 6–8 years predicted PEB (p<0.05).

Hence, it was concluded that "resin infiltration positively influenced the structural integrity maintenance of MIH-affected teeth by decreasing the risk of enamel breakdown over18 months follow-up."

Resin infiltration proved to be a more efficacious intervention to maintain the structural integrity of MIH-affected teeth than fluoride varnish therapies, they further added.