Stannous fluoride toothpaste helps protect against enamel erosions: Study

Written By :  Dr. Nandita Mohan
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2021-01-07 11:00 GMT   |   Update On 2021-01-07 11:01 GMT

According to recent findings, it has been observed that the use of these bioavailable SnF2 toothpaste, as part of daily oral hygiene regimen will provide patients with enamel erosion protection, combined with alleviation of Dentinal hypersensitivity pain when present thereby improving the quality of life.

The study is published in the Journal of Dentistry.

Dentine hypersensitivity (DH) and enamel erosion are prevalent oral conditions. However, their association is seldom seen in the literature. Therefore, Nicola X.West and associates from the Department of Periodontology, Bristol Dental School, University of Bristol, UK conducted this present study to compare the effect of bioavailable gluconate-chelated stannous fluoride (SnF2) toothpaste with control toothpaste for treatment of dentine hypersensitivity (DH) and enamel erosion.

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The authors shortlisted eligible studies that were Randomised Controlled Trials (RCTs) which aimed at investigating the bioavailable gluconate chelated SnF2 toothpaste efficacy when compared to controls in adult participants. This was measured following tactile (Yeaple force) and/or evaporative stimuli (Schiff score) in-vivo for a duration of more than 2 months (DH); or by erosive tooth wear (profilometry) from in-situ samples carried out for a duration of 10–15 days.

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Out of the whole team of researchers, two authors independently assessed eligibility and resolved disagreements by discussion. A meta-analysis was undertaken and Risk of Bias (RoB) assessed using the Cochrane collaboration RoB tool for randomized parallel-group and cross-over trials.

The following results were noted-

  1. Fourteen RCTs (1287 participants) assessed DH relief and Six RCTs (184 participants) enamel erosion protection.
  2. For DH, SnF2 toothpastes provided a 57 % (evaporative air) and 142 % (tactile) benefit versus negative controls (sodium fluoride/monofluorophosphate, 8 studies; p < 0.001).
  3. Compared to positive controls (potassium nitrate or arginine, 6 studies), a 22 % advantage (p = 0.036) was seen for evaporative air.
  4. In erosion studies, SnF2 toothpaste provided an 83 % benefit versus control toothpaste (arginine or sodium fluoride; p < 0.001) with a change (95 %CI) in average surface profilometry level (μm) of -2.02(-2.85, -1.20).

Hence, the authors concluded that "the use of these bioavailable SnF2 toothpaste, as part of a daily oral hygiene regimen, will provide patients with enamel erosion protection, combined with the alleviation of DH pain when present, improving quality of life."


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Article Source : Journal of Dentistry

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