Researchers have found in a new study that tooth loss is associated with higher mortality from several specific causes, including cardiovascular disease, respiratory disease, and infections. The analysis suggests that the absence of natural teeth may contribute to systemic health risks, potentially due to impaired nutrition, chronic inflammation, or altered oral microbiota. The study highlights that maintaining oral health is not only critical for quality of life but may also influence long-term survival outcomes. Importantly, the authors noted that the use of dental prostheses appeared to mitigate some of this increased mortality risk, emphasizing the protective role of functional oral rehabilitation.
Here is the thing — the findings underline the interconnectedness of oral and systemic health. While tooth loss is often treated as an isolated dental issue, this study provides compelling evidence that it has far-reaching health implications. Dental prostheses, including dentures and implant-supported restorations, can restore masticatory function, improve nutritional intake, and support overall health, thereby potentially reducing the risk of cause-specific mortality. The researchers also observed that timely intervention with prosthetic solutions may be particularly beneficial for older adults and individuals with pre-existing chronic conditions. This suggests that dental care should be integrated into broader public health strategies targeting long-term health and survival.
What this really means is that preventive dentistry and timely prosthetic rehabilitation could play a key role in reducing premature death linked to oral health deficits. The authors advocate for greater awareness of tooth loss as a modifiable risk factor and call for regular dental check-ups, prompt treatment of tooth loss, and provision of appropriate prosthetic care. Further research is needed to clarify the biological mechanisms connecting tooth loss to systemic mortality and to determine the most effective prosthetic interventions. Nonetheless, this study provides robust evidence supporting the health benefits of maintaining functional dentition and reinforces the importance of comprehensive dental care throughout the lifespan.
Keywords: tooth loss, mortality, dental prostheses, systemic health, cardiovascular disease, respiratory disease, nutrition
Reference : Zhang, H., Li, J., Wang, X., et al. (2025). Tooth loss raises cause-specific mortality risk, but prostheses may reduce it: Study.
Scientific Reports, 15, 24357.
https://doi.org/10.1038/s41598-025-24357-1
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