Tricalcium phosphate good option for reducing dentin sensitivity

The 4-week double-blind clinical trial to manage dentin hypersensitivity (DH) using different desensitizing toothpastes was conducted. 53 participants with dentin hypersensitivity were enrolled in this trial.

The participants were randomized into 3 groups: Group N; no active ingredient-containing toothpaste (Pleasia fluoride-free), Group SC; a toothpaste containing strontium chloride (Sensodyne Original), and Group TP; a toothpaste containing tricalcium phosphate (Vussen S). They were instructed to brush their teeth manually for 3 min, 3 times per day for 4 weeks with the allocated toothpastes, and were assessed at baseline (0), 2, and 4 weeks, respectively. Schiff sensitivity score was recorded to 3 different stimuli (air-blast, cold, and acid) at each assessment.

Overall dentin hypersensitivity was also assessed using a visual analog scale (VAS). The longer participants used the toothpastes, the greater reduction in dentin hypersensitivity in all groups to the three stimuli. Group TP demonstrated significant reduction of dentin hypersensitivitycompared to group N for air-blast and cold stimuli. Group TP showed significantly lower VAS than group N and SC. Tricalcium phosphate containing toothpaste used in this trial was most useful to reduce dentin hypersensitivity.

It can be one of the treatment options that alleviate dentin hypersensitivity.

The authors concluded that the use of toothpaste containing tricalcium phosphate can reduce dentin hypersensitivity (DH) effectively. If clinicians use it properly, it can be the first option to treatment of initial DH or an alternative to composite resin restoration at cervical lesion.

Reference:

Jang, JH., Oh, S., Kim, HJ. et al. A randomized clinical trial for comparing the efficacy of desensitizing toothpastes on the relief of dentin hypersensitivity. Sci Rep 13, 5271 (2023). https://doi.org/10.1038/s41598-023-31616-6