Monitoring of immune and inflammatory indicators crucial for alopecia areata diagnosis: Study
China: A recent study in the Journal of Cosmetic Dermatology has stated that although the etiopathogenesis of alopecia areata (AA) is not clear but monitoring the levels of T3, T4, thyroid antibodies (TPOAbs), antinuclear antibodies (ANA), and 25 (OH)D is crucial in alopecia areata cases.
Alopecia areata is a common autoimmune disorder that often results in unpredictable hair loss. It affects roughly 6.8 million people in the United States. Yamei Gao, Department of Dermatology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China, and colleagues aimed to evaluate several parameters related to autoimmunity and inflammation in AA patients and to evaluate their association with this disease.
The study included a total of 672 eligible AA patients and 580 age- and sex-matched healthy individuals who were treated at a third-class hospital in Hefei from January 2016 to May 2020. Data for serum C-reactive protein (CRP), 25-hydroxy vitamin D (25(OH)D), T3, T4, thyroid-stimulating hormone (TSH), thyroid antibodies (TPOAbs and TGAbs), antinuclear antibodies (ANA), complements (C3, C4), and several immunoglobulins (IgA, IgM, and IgG) were collected for this study.
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