Spironolactone safe treatment option for breast cancer therapy induced alopecia
Spironolactone a heart failure medication is often used off-label to treat female androgenetic hair loss because of its peripheral antiandrogen effects.
Researchers have found that Spironolactone used for the treatment of endocrine therapy–induced alopecia in breast cancer survivors doesn't increase risk of recurrence of the malignancy in a large retrospective study. The study has been published in the Journal Breast cancer research and treatment.
The researchers considered all published studies from January 1978 through April 2018 using databases such as PubMed, Google Scholar, and Science Direct. 47 studies were included in this review.
The researchers initially compared 746 women who went on spironolactone after their breast cancer diagnosis with 28,400 female breast cancer patients who didn't take the drug. The primary outcome was recurrent breast cancer within 2 years after diagnosis.
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