Adrenalectomy may improve Diabetes symptoms in nearly half of primary aldosteronism patients with DM
China: Researchers from China found that Adrenalectomy was successful in remitting and improving Diabetes in nearly half of primary aldosteronism (PA) patients with Diabetes. Longer duration of hypertension, a higher concentration of urinary magnesium and higher 24 h urinary potassium could hinder the remission and improvement, but examination of urinary electrolytes can predict the outcomes of Diabetes in PA patients. The study results were published in the journal BMC Endocrine Disorders.
Primary aldosteronism (PA) is characterized by hypertension, excessive aldosterone excretion, and low serum potassium. Adrenalectomy and mineralocorticoid receptor antagonists are the recommended therapies for PA patients. Recent literature showed that adrenalectomy would improve insulin secretion in PA patients despite some studies stating that blood glucose levels did not alter. Hence Chinese researchers from the West China Hospital, Sichuan University conducted a study to evaluate the outcome of diabetes after adrenalectomy and determine the factors associated with that in PA patients.
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