Age Matters: Study Finds Divergent Risks of HbA1c Levels in Diabetes Patients with Triple-Vessel Disease
China: A recent cohort study has shed light on the critical link between glycated hemoglobin (HbA1c) levels and long-term outcomes in patients grappling with diabetes and triple-vessel coronary disease (TVD). The research, conducted across diverse age brackets, underscores significant variations in prognosis based on age, challenging conventional medical wisdom on diabetes management.
The study, published in Diabetes Research and Clinical Practice, revealed variations in the relationship between HbA1c levels and endpoint events among patients with triple-vessel coronary disease and diabetes of different ages.
"In younger patients, increased HbA1c levels were associated with a higher risk of major adverse cardiovascular and cerebrovascular events (MACCE) and death, while in older patients, excessively low HbA1c levels (HbA1c < 6 %) tied to a higher risk of death and MACCE," the researchers reported.
Lei Song, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, China, and colleagues aimed to investigate the correlation between HbA1c and adverse prognostic events in patients with diabetes and TVD.
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