Vitamin D Deficiency Linked to Multiple Diabetic Complications: Study

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2025-08-13 04:30 GMT | Update On 2025-08-13 11:00 GMT

A new study published in Nutrition and Health has found that Vitamin D deficiency is independently associated with a range of serious diabetic complications, including neuropathy, nephropathy, retinopathy, ischemic heart disease (IHD), and diabetic foot disease (DFD).

The cross-sectional analysis highlights a significant link between low serum 25-hydroxyvitamin D levels and the presence of these complications in individuals with type 2 diabetes. Researchers suggest that Vitamin D may play a role in the underlying pathophysiology of these conditions, possibly through mechanisms involving chronic inflammation, oxidative stress, and endothelial dysfunction.

The findings emphasize the need to monitor Vitamin D status more routinely in diabetic patients, especially those already showing signs of microvascular or macrovascular damage. While the study does not establish direct causality, it contributes to the growing body of evidence that Vitamin D deficiency may be a modifiable risk factor in diabetes-related morbidity.

The authors recommend further prospective studies and clinical trials to evaluate whether correcting Vitamin D deficiency could help prevent or delay the onset of such complications. Given the widespread prevalence of both diabetes and Vitamin D deficiency globally, these insights may carry significant implications for public health and chronic disease management strategies.

Reference:

Zafar, M. I., et al. (2024). Association of vitamin D deficiency with diabetes-related complications: A cross-sectional study. Nutrition and Health. https://doi.org/10.1177/02601060251359708

Article Source : Nutrition and Health

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Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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Vitamin D Deficiency Linked to Multiple Diabetic Complications: Study

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