Closed-Loop Control system insulin administration effective for blood sugar control among kids with type 1 diabetes

A new study by Mosleh Jabari showed that in adolescents with type 1 diabetes, Closed-Loop Control (CLC) insulin administration had considerably higher day and night effectiveness and safety than Sensor-Augmented Insulin Pump (SAP) treatment. The findings of this study were published in Nature Scientific Reports.

Children suffering with diabetes mellitus (DM), which is a collection of metabolic illnesses rather than a single condition characterized by persistent hyperglycemia, have been a global concern. Glycemic objectives for children with T1DM have gotten increasingly stringent over time, and the average blood glucose (sugar) level goal for all children, regardless of age, is currently 70 to 120 mg/dL. Recent technological breakthroughs, such as insulin pumps and ongoing glucose monitoring devices, have transformed T1DM management.

A traditional therapy is the Sensor-Augmented Insulin Pump, which mimics pancreatic insulin production by continuous subcutaneous insulin infusion (CSII). The CLC insulin delivery systems are distinguished by real-time glucose-responsive administration of insulin and the combination of glucose-sensing and insulin-delivery components.

The goal of this meta-analysis is to evaluate the efficacy and safety of CLC to SAP in adolescents with type 1 diabetes (T1DM) by comparing glycemic results and hypoglycemia episodes.