Diabetics with low HDL-C levels prone to peritoneal dialysis-related peritonitis
China: Patients with diabetes and concurrent low HDL-C levels are at a higher risk for peritoneal dialysis-related peritonitis (PDRP) in peritoneal dialysis (PD) patients, shows a recent study in the journal Diabetology & Metabolic Syndrome.
In patients undergoing peritoneal dialysis, low levels of high-density lipoprotein cholesterol (HDL-C) and diabetes are common. Considering this, Yajuan Huang, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, and colleagues aimed to examine the association between the coexistence of diabetes and a low level of HDL-C and the first episode of PDRP in patients with PD.
For this purpose, the researchers retrospectively investigated patients with PD from January 1, 2003, to May 31, 2020, in four PD centers. PD patients were categorized into four groups: no comorbidities, low HDL-C only, diabetes only, and diabetes plus low HDL-C. They collected and compared the clinical and laboratory baseline data of the four groups. Multivariate Cox regression analysis was used to analyze the association between diabetes coexisting with low HDL-C levels and the first episode of PDRP.
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