Probiotics supplementation promising adjuvant therapy for patients with type 2 diabetes
China: A recent study published in the Journal of Translational Medicine has supported the favourable effects of probiotics supplementation in patients with type 2 diabetes mellitus (T2DM), implying it to be a promising adjuvant therapy for T2DM patients.
The systematic review and meta-analysis revealed that Bifidobacterium and food-type probiotics had higher glucose-lowering effects than other probiotic genera and vehicle types used for probiotic delivery. Probiotic intervention may be of more benefit for patients with a higher BMI concerning glycemic control.
Type 2 diabetes accounts for about 90% of all diabetes cases, leading to life-threatening and costly complications and reduced life expectancy. There exists no radical cure for T2DM, and its treatment relies on the use of anti-diabetic drugs for the long term. Therefore, exploring new methods that may effectively delay or even reverse T2DM progression is essential.
Recent research has demonstrated that gut microbiota plays a critical role in maintaining host homeostasis and the pathogenesis of T2DM. Probiotics are microbial dietary supplements that modify the gut microbiota. Some RCTs (randomized controlled trials) have investigated the effects of probiotics on glycemic control in patients with type 2 diabetes. However, evidence is inconsistent from clinical trials on the effects of probiotics supplementation on blood sugar control.
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