Stress hyperglycemia ratio predicts in-hospital mortality in CAD patients: Study
China: In patients with coronary artery disease (CAD), stress hyperglycemia ratio (SHR) is significantly associated with in-hospital mortality, a recent study in Cardiovascular Diabetology has found.
The findings indicate that SHR could effectively predict in-hospital mortality among CAD patients, particularly for patients with pre-diabetes Mellitus (DM) and DM.
In patients with acute coronary syndrome (ACS), there is a strong association between stress hyperglycemia and poor clinical outcomes. The SHR, recently, has been proposed to represent relative hyperglycemia. However, studies exploring the relationship between SHR and mortality in CAD are limited. Considering this, Wei Xu and the research team from China conducted the study to clarify the link between SHR and in-hospital mortality in CAD patients.
The study enrolled 19,929 CAD patients who were hospitalized at Beijing Hospital. Patients with an eGFR (estimated glomerular filtration rate) < 30 ml/min, missing blood glucose/HbA1c data, or cancer were excluded. Therefore, the final analysis included 8,196 patients. Based on tertiles of SHR, the patients were divided into three groups: T1 group with SHR < 0.725 (n = 2,732), T2 group with 0.725 ≤ SHR < 0.832 (n = 2,730), and T3 group with SHR ≥ 0.832 (n = 2,734). In-hospital mortality was the primary endpoint.
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