Vitamin D Deficiency Linked to Diabetic Peripheral Neuropathy in Elderly Diabetes Patients: Study
Vitamin D deficiency (VDD) has been implicated in various health conditions, including diabetic peripheral neuropathy (DPN) in individuals with type 2 diabetes mellitus (T2DM). A recent study investigated the association between VDD and DPN in elderly T2DM patients, shedding light on the potential role of vitamin D in neuropathic complications. This study was published in the journal of Diabetes Research and Clinical Practice by Sijia Fei and colleagues.
DPN is a common complication of T2DM, characterized by nerve damage leading to sensory and motor deficits. VDD has emerged as a potential risk factor for DPN, but the mechanisms underlying this association remain unclear. Understanding the relationship between VDD and DPN could provide insights into novel therapeutic strategies for managing neuropathic complications in T2DM.
The study included 257 elderly patients with T2DM and utilized propensity score matching to balance demographic and diabetes-related factors. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured to assess VDD, defined as levels below 20 ng/ml. Nerve conduction studies were conducted to evaluate both large and small nerve fiber lesions.
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