Vitamin D levels associated with improved islet function in type 2 diabetes patients: Study
China: A recent study published in the BMC Endocrine Disorders suggested a positive relationship between the vitamin D status and modified HOMA-β. According to the study, an increase in vitamin D or vitamin D supplementation may be related to delayed pancreatic β cell functional decline and improved modified HOMA-β function and vice-versa.
Homeostatic model assessment (HOMA) is a method for the assessment of β-cell function and insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concentrations.
Widespread type 2 diabetes mellitus (T2DM) has caused a burden worldwide. Evaluation of islet function is important for patients with T2DM because it is usually used to assess the progress of T2DM and to guide drug usage. A group of researchers from China performed a study to explore the relationship between vitamin D status and islet function in patients with type 2 diabetes mellitus.
The participants were recruited from Hebei General Hospital. Basic characteristics and blood indicators were collected after fasting overnight. The data were analyzed statistically using SPSS 22.0. Analysis of variance, a nonparametric test, or a trend Chi-square test was used for the comparisons. The association between 25-hydroxy vitamin D and modified homeostasis model assessment-β was assessed using multivariate ordinal logistic regression.
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