Vitamin D levels associated with improved islet function in type 2 diabetes patients: Study

The results of the study are as follows:

• One hundred seventy-four patients aged 26 to 79 years with type 2 diabetes mellitus were included in this study.
• Patients with vitamin D deficiency had a lower modified homeostasis model assessment-β level compared with those without vitamin D deficiency.
• There were differences in body mass index, diabetes course, glycosylated hemoglobin, fasting blood glucose, fasting blood C-peptide, triglyceride, and 25-hydroxy vitamin D among different modified homeostasis model assessment-β groups based upon the tertiles. 25-hydroxy vitamin D, as continuous or categorical variables, was positively related to modified homeostasis model assessment-β whether or not cofounding factors were adjusted.

The researchers concluded that there is an association between increased 25-hydroxy vitamin D levels and improvement in modified homeostasis model assessment-β function in patients with type 2 diabetes mellitus. Increase in or supplementation of vitamin D may be related to improved modified HOMA-β function and delayed pancreatic β cell functional decline.

Reference:

The relationship between vitamin D status and islet function in patients with type 2 diabetes mellitus by Hang Zhao et al published in the BMC Endocrine disorders.

https://doi.org/10.1186/s12902-021-00862-y