Vitamin K supplementation may reduce risk of development of type 2 diabetes
China: A systematic review and meta-analysis published in the journal Food and Function has shed light on the relationship between vitamin K and type 2 diabetes mellitus (T2DM).
The researchers showed a significant effect of vitamin K supplementation on the regulation of fasting blood sugar (FBS) and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) in the population. Further, vitamin K was associated with a reduced risk of type 2 diabetes development.
"A meta-analysis of seven studies comprising 813 participants found vitamin K supplementation significantly reduced FBS (SMD = −0.150 mg dl−1) and HOMA-IR (SMD = −0.200), but not FINS," the researchers wrote.
Previous studies have demonstrated the potential role of vitamin K supplementation in the treatment and prevention of many diseases. However, there is a controversy around the effect of vitamin K supplementation on blood glucose. Therefore, Boyang Qu, Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China, and colleagues aimed to evaluate the effects of vitamin K supplementation on glycemia-related indicators, including fasting blood sugar, fasting insulin (FINS), and Homeostasis Model Assessment of Insulin Resistance. They also evaluated the potential association between vitamin K and type 2 diabetes risk.
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