Is COVID 19 Vaccination linked to Risk of Hearing Loss, explore JAMA studies
Written By : MD Bureau
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-03-02 03:30 GMT | Update On 2022-03-02 03:31 GMT
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Study 2:
Dr Yoav Yanir and his team conducted a retrospective, population-based cohort study to assess the association between the BNT162b2 mRNA COVID-19 (Pfizer-BioNTech) vaccine and SSNHL.
The major outcome assessed was the outcome was SSNHL based on International Classification of Diseases, Ninth Revision (ICD-9) codes in conjunction with concurrent prednisone dispensing. Observed cases of SSNHL, occurring within 21 days after each of the first and second vaccine doses, were compared with the expected cases based on the experience of the population in 2018 and 2019. They then estimated the standardized incidence ratios (SIRs) and attributable risks.
- Upon analysis, the researchers found that the incidence rate of sudden sensorineural hearing loss was 60.77 per 100 000 person-years after the first dose and 56.24 per 100 000 person-years after the second dose.
- They noted that the estimated SIRs were more pronounced in female patients aged 16 to 44 years (SIR, 1.92; 95% CI, 0.98-3.43) and female patients 65 years or older (SIR, 1.68) after 1st vaccine dose.
- They observed the highest estimated SIR in male patients 16 to 44 years (SIR, 2.45) after the second dose.
- They noted that the attributable risks were generally small, and the results were similar when 2019 was used as a reference to estimate the expected number of SSNHL cases.
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