Open diverticulectomy superior to other surgery treatments for Zenker diverticulum: JAMA

For the purpose, the researchers searched published literature on September 21, 2018. The review included cohort studies or randomized clinical trials. Studies that included patients needing revision surgery or undergoing an alternative technique were excluded. 

The Preferred Reporting Items for Systematic Reviews and Meta-analyses–Network Meta-analyses (PRISMA-NMA) checklist was used to report the study findings. Two authors independently reviewed the studies.

The primary outcome measure was the incidence of persistent or recurrent symptoms following surgery. The primary study outcome was planned before data collection began. 

The search generated 529 studies. After applying inclusion and exclusion criteria, 9 cohort studies remained, consisting of 903 patients treated with either laser-assisted diverticulotomy (n = 283), transcervical diverticulectomy (n = 150), or stapler-assisted diverticulotomy (n = 470). 

"This systematic review and meta-analysis compared 3 common techniques for treating ZD. The open approach showed a decreased likelihood of persistent or recurrent symptoms following surgery compared with the 2 other technique," concluded the authors. 

The review titled, "Comparison of Surgical Treatments for Zenker Diverticulum: A Systematic Review and Network Meta-analysis," is published in the journal JAMA Otolaryngology-Head & Neck Surgery.

DOI: https://jamanetwork.com/journals/jamaotolaryngology/article-abstract/2773739