Statin Use effective in Postoperative Outcomes for Chronic Rhinosinusitis: study

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-09-21 15:00 GMT   |   Update On 2022-09-22 09:03 GMT

Statin Use Beneficial in Postoperative Outcomes for Chronic Rhinosinusitis according to a recent study published in the Annual Meeting and OTO Experience Statin use is associated with a decreased rate of uncontrolled disease and revision surgery in patients with chronic rhinosinusitis (CRS) who had endoscopic sinus surgery (ESS), according to study results presented at the...

Login or Register to read the full article

Statin Use Beneficial in Postoperative Outcomes for Chronic Rhinosinusitis according to a recent study published in the Annual Meeting and OTO Experience

Statin use is associated with a decreased rate of uncontrolled disease and revision surgery in patients with chronic rhinosinusitis (CRS) who had endoscopic sinus surgery (ESS), according to study results presented at the American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) 2022 Annual Meeting and OTO Experience, held from September 10-14, 2022 in Philadelphia, Pennsylvania.

Researchers assessed the effects of statins on postoperative outcomes and recurrence in patients with CRS who underwent ESS from 2017 to 2021.

A total of 380 patients (82 patients were taking statins and 298 patients were not taking statins) who completed follow-up for more than 3 months were enrolled. The researchers compared subjective symptoms, postoperative endoscopic scores, and olfactory function outcomes between the statin treatment group and the statin-free group. Multivariate analysis was conducted to assess the effect of statins on postoperative outcomes as determined by the necessity of revision surgery.

Compared with patients with CRS who were not taking statins, those who were taking statins had a statistically significant decrease in the rate of uncontrolled disease (43.6% vs 34.5%, respectively; P =.032).

Statin use was significantly associated with a reduction in the rate of revision surgery (odds ratio, 0.412; P <.05; 95% CI, 0.179-0.951) according to multivariate analysis. At 12 months post-surgery, the discharge score of the Lund-Kennedy scoring system indicated significant improvement in patients receiving statins vs those not taking statins (P <.05).

"Statin medication showed significant beneficial effects in improving postoperative outcomes after ESS," the researchers stated.

Reference:

Min J-Y, Min HK. The effect of statin medication on postoperative outcomes in patients with chronic rhinosinusitis. Abstract presented at: AAO-HNSF 2022 Annual Meeting and OTO Experience; September 10-14, 2022; Philadelphia, PA.

Keywords:

Min J-Y, Min HK, effect, statin, medication, postoperative, outcomes, patients chronic, rhinosinusitis, Annual Meeting and OTO Experience

Tags:    

Disclaimer: This site is primarily intended for healthcare professionals. Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement/treatment or prescription. Use of this site is subject to our terms of use, privacy policy, advertisement policy. © 2024 Minerva Medical Treatment Pvt Ltd

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News