Administration of Lactated Ringer's solution in first 24 hours of hospitalization may improve outcomes in Acute Pancreatitis
Recent pilot trials in acute pancreatitis (AP) found that lactated ringers (LR) usage may result in decreased risk of moderately severe/severe AP compared with normal saline, but their small sample sizes limit statistical power
In a recent study, researchers investigated whether lactated Ringer's (LR) solution improves outcomes in 999 patients with a history of acute pancreatitis (AP).
According to this study, using the LR solution during the first 24 hours of hospitalization is associated with reduced odds of moderately severe/severe AP compared with normal saline usage after adjusting for confounding variables.
According to a recent pilot trial, researchers have shown that in acute pancreatitis patients, lactated ringers (LR) decreases the risk of moderately severe/severe AP compared to normal saline. The main limitation of these studies is related to small sample sizes limiting statistical power.
In this study, the team investigated whether LR usage improves outcomes in AP in those patients enrolled at 22 international sites (2015 - 2018).
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