Can Tea consumption reduce risk of colorectal cancer?
Tea is recognized as a chemical preventive agent for some diseases. Previous evidence has already mentioned some protective ingredients in tea that could reduce CRC. However, according to the latest study, tea reduces the risk of colon cancer by 24%, but the estimate is uncertain. The actual effect on risk may range from a reduction of 51% to an increase of 18%. Still, regional and population differences may cause differences, says Dr Yu Huang and colleagues in a recent study published in BMC Gastroenterology.
Tea polyphenols can inhibit tumour development by promoting tumor cell apoptosis, inhibiting proliferation and angiogenesis via regulating signalling pathways like Ras-MAPK. These findings remain controversial. Many studies have shown that tea consumption has no association with a decreased risk of CRC.
Researchers systematically assessed the association between tea consumption and CRC risk in the present meta-analysis from databases like Cochrane Library, Embase, PubMed, and Web of Science. The literature screening was done based on inclusion and exclusion criteria. The random effect model was determined, and odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.
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