Circadian syndrome associated with prevalence of gallstones in non smokers: BMC Study

A new study published in the journal of BMC Gastroenterology showed that the occurrence of gallstones was strongly correlated with circadian syndrome, especially in those who did not smoke. About 10% to 20% of individuals worldwide suffer from gallstone disease (GSD) that is one of the most frequent digestive problems in the general population. Symptoms of GSD include nausea, vomiting, loss of appetite, and discomfort in the stomach and abdomen.
Higher incidence and mortality rates from common chronic illnesses such diabetes, hypertension, cardiovascular disease, and gastrointestinal malignancies have been associated with gallstones. The internal circadian clock generates circadian rhythms which control important bodily physiological processes including metabolism, are produced by transcription factors and gene expression. Chronic conditions including kidney stones, overactive bladder, and stroke are associated with the circadian syndrome. However, nothing is known about the connection between gallstones and circadian disorders. This population-based study by Fenping Liang and colleagues was set to determine if circadian syndrome is linked to gallstones.
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