Cuff- and cap-assisted colonoscopy of no benefit over high-definition colonoscopy for adenomas: Study

USA: A new study showed that even with high-detector endoscopists, there is no substantial benefit in utilizing either distal attachment device (CF or CP) over high-definition white light colonoscopy (HDWLE). In the screening population, the Endocuff may offer an advantage. This study was conducted by Prateek Sharma and the team, the results of which were published in Clinical Gastroenterology and Hepatology, on 31st December 2021.

When compared to high-definition white light colonoscopy, mucosal exposure devices, including distal attachments such as the cuff and cap, have shown varying outcomes in enhancing adenoma detection rates (ADRs) when compared to HDWLE.

Researchers conducted a prospective, multicenter randomized controlled experiment in individuals having screening or surveillance colonoscopy to compare HDWLE to two types of distal attachments: cuff (CF) (Endocuff Vision) or cap (CP) (Reveal). ADR was the key result. Secondary outcomes were the number of adenomas detected per colonoscopy, the incidence of advanced adenoma and sessile serrated lesion detection, right-sided ADR, withdrawal time, and adverse events. Using the statistical programme Stata version 16, continuous variables were compared using the Student's t test, and categorical variables were compared using the chi-square or Fisher's exact test. A P value of.05 was deemed significant.