Daily aspirin can significantly reduce liver fat content in metabolic dysfunction-associated steatotic liver disease: Study
USA: A recent clinical trial revealed that six months of daily low-dose aspirin significantly reduced hepatic fat quantity compared with placebo in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
The most common chronic liver disease is metabolic dysfunction-associated steatotic liver disease characterized by an increased buildup of fat in the liver due to factors such as obesity and type 2 diabetes.
Such elevated fat poses serious health risks, but the clinical trial published in JAMA and conducted by investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, reveals that daily aspirin can significantly reduce liver fat content.
“Since MASLD is estimated to affect up to a third of U.S. adults, aspirin represents an attractive potential low-cost option to prevent progression to cirrhosis or liver cancer, the most feared complications of MASLD,” said senior author Andrew T. Chan, MD, MPH, a gastroenterologist and chief of the Clinical and Translational Epidemiology Unit at Massachusetts General Hospital.
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