Enhanced-image endoscopy improves detection of upper GI cancers, finds study

Researchers from National Hospital Organization Hakodate National Hospital, Hakodate, Hokkaido, Japan identified 1,502 patients with known previous or current cancer of the GI tract to compare the performance of LCI with WLI in detecting neoplastic lesions in the upper GI tract. The patients were randomly assigned to WLI followed by LCI examination (WLI group) or LCI followed by WLI examination (LCI group), with the patients just about evenly divided into each group. The researchers found that the doctors using LCI diagnosed 1.67 more neoplastic lesions in the first examination than they did with WLI. The proportion of patients with overlooked neoplasms was also lower in the LCI group than in the WLI group. The authors conclude that LCI is more effective than WLI for detecting neoplastic lesions in the pharynx, esophagus, and stomach. Their results suggest that many neoplastic lesions are being overlooked by conventional white light endoscopy performed in routine clinical practice. They say to reduce the rate of overlooking neoplasms, LCI should ideally be applied in clinical practice.

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https://www.acpjournals.org/doi/10.7326/M19-2561