Gut Microbiome Composition associated with future onset of Crohn's Disease in Healthy First-Degree Relatives
Written By : Dr. Shravani Dali
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-06-04 14:30 GMT | Update On 2023-06-05 06:49 GMT
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Gut Microbiome Composition is associated with future onset of Crohn's Disease in Healthy First-Degree Relatives suggests a new study published in the Gastroenterology
The cause of Crohn’s Disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of CD patients have catalogued alterations in the gut microbiome composition; however, these studies fail to distinguish if the altered gut microbiome composition is associated with initiation of CD or is the result of inflammation or drug treatment.
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