H. pylori infection associated with abdominal obesity in younger adults: BMC

Further analysis showed that the adjusted association between abdominal obesity (defined by WHtR) and H. pylori seropositivity was significant in subjects under 50 years of age, but, this association was not significant in individuals over 50 years. Moreover, metabolically healthy obesity (obesity without metabolic syndrome) was less likely to be associated with H. pylori infection in the older age group. The study found no significant link between general obesity and H. pylori seropositivity. This suggests that abdominal fat plays a more crucial role in the association with H. pylori infection than overall body fat, in younger individuals.

The findings of this study highlight the importance of considering abdominal obesity when examining the relationship between H. pylori infection and obesity. The significant association found in younger adults points to the growing need for age-specific approaches in understanding and potentially managing H. pylori infection. Further research and comprehensive studies could add valuable insights to the ongoing investigation of how obesity and H. pylori infection are interconnected and also to address the related health issues in younger populations.

Source:

Chen, D., Wang, S., Yang, W., Lu, H., & Ren, Q. (2024). Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999–2000. In BMC Infectious Diseases (Vol. 24, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12879-024-09409-7