HOMA-IR Identified as Independent Predictor of Liver Fibrosis in MAFLD, suggests study
Written By : Dr Riya Dave
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2025-09-04 02:45 GMT | Update On 2025-09-04 07:05 GMT
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According to a recent study published in Scientific Reports insulin resistance as assessed by the homeostatic model assessment for insulin resistance (HOMA-IR) has been identified as an independent predictor of substantial liver fibrosis in metabolic dysfunction-associated fatty liver disease (MAFLD) patients. This observation underscores the significance of adding HOMA-IR to the criteria recently suggested metabolic dysfunction-associated steatotic liver disease (MASLD) eliminating HOMA-IR as a criterion for metabolic dysregulation. In this analysis, HOMA-IR was robustly linked with severe stages of liver fibrosis, regardless of diabetes status or body mass index (BMI). The study was conducted by Yasser F. and colleagues.
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