Polysaccharide hemostatic powder use as effective as conventional endoscopic therapy for treating peptic ulcer bleeding
Polysaccharide hemostatic powder use is not inferior to conventional endoscopic therapy for the treatment of peptic ulcer bleeding suggests a new study published in the Clinical Gastroenterology and Hepatology
Hemostatic powders have been clinically used in the treatment of gastrointestinal bleeding. We investigated the non-inferiority of a polysaccharide hemostatic powder (PHP), compared with conventional endoscopic treatments, for peptic ulcer bleeding (PUB).
This study was a prospective multicenter randomized open-label controlled trial at four referral institutions. We consecutively enrolled patients who had undergone emergency endoscopy for PUB. The patients were randomly assigned to either a PHP or conventional treatment group. In the PHP group, diluted epinephrine was injected, and the powder was applied as a spray. Conventional endoscopic treatment included the use of electrical coagulation or hemoclipping after injection of diluted epinephrine.
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