Sarcopenia linked to higher mortality rates in individuals with NAFLD, claims study
In a recent development, among a nationally representative sample of US adults, sarcopenia has been associated with a higher risk for all‐cause, cancer‐ and diabetes‐related mortality in individuals with NAFLD.The findings have ben put forth in the Liver International.
Nonalcoholic fatty liver disease (NAFLD) has increasingly been recognized as the most prevalent chronic liver disease in the world, with an estimated prevalence of 25% globally.
In previous studies, Nonalcoholic fatty liver disease (NAFLD) has been associated with sarcopenia. Sarcopenia is defined as a progressive loss of skeletal muscle mass, function, and strength . Studies have showed that sarcopenia increases the risk of diabetes, dyslipidemia,
cardiovascular disease , and liver disease .NAFLD and sarcopenia share key pathogenetic pathways, including insulin resistance, chronic systemicinflammation, and vitamin D deficiency.However, mortality in the setting of NAFLD‐related sarcopenia remains undefined. Therefore, a team of researchers undertook a study with the aim to determine the all‐cause and cause‐specific mortality from sarcopenia among adults with NAFLD in the United States (US).
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