Severe NAFLD tied to subclinical coronary atherosclerosis risk: Study
Severe Non-alcoholic Fatty liver disease is associated with a high risk of subclinical atherosclerosis, independent of Framingham's risk score (FRS) and body fat percentage, finds a new study published in the Journal of clinical gastroenterology and hepatology.
The subclinical coronary atherosclerosis was measured by coronary CT Angiography (CTA) and coronary artery calcium (CAC) scans.
Researchers lead by Min Seo Kim in a retrospective study tried to elucidate the link between the subclinical coronary artery disease (CAD) and NAFLD severity in real-world Asian patients. In 2018, total participants were 972 who were undergoing regular health inspections, abdominal sonography and angiography of coronary CT but in the final cohort 812 adults were included.
There were statistically significant differences in specific baseline characteristics, including laboratory and anthropometric measurements and coronary artery findings.
The prevalence of susceptible plaques and subclinical coronary atherosclerosis substantially increased with NALFD severity.
In terms of subclinical coronary atherosclerosis, no significant variances were found in the post-holder analysis with mild vs. moderate NAFLD and normal vs. mild NAFLD.
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