Study highlights Gender Differences in Gastroparesis Outcomes: Males Face Higher Risks

A new study published in the journal of Cureus showed that while female patients with gastroparesis (GP) have longer hospital stays and higher VTE risk, male patients experience significantly worse clinical outcomes, including higher rates of ARF, sepsis, shock, ICU admissions, and in-hospital mortality. Despite females being hospitalized more often for GP, the study highlights the need for more aggressive management in male patients to reduce morbidity and mortality.

About 60% of people globally suffer from epistaxis, a frequent ailment in just 6–10% of instances that need for prompt medical attention. Mucosal dryness, hypertension, allergic rhinitis, and diabetes are contributing factors to epistaxis, which is usually produced by burst nasal mucosa vessels. It can also arise spontaneously or as a result of trauma, systemic disorders, or as a side effect of drugs such as anticoagulants. One relatively recent method of treating epistaxis is microwave ablation (MWA). 

The effectiveness and safety of utilizing MWA to treat frequent nosebleeds are investigated in this systematic study. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were followed throughout its execution. For this systematic review, publications were found and compiled using two databases: PubMed and EMBASE.

A total of 2,691 articles covering the years 1947–2023 were found using the search keywords. Following screening, 5 observational studies, one case series, and one randomized control trial met the requirements for inclusion. The patients who received MWA therapy observed little side effects.

This study found 852 of the 876 patients who had MWA reported to have no recurrence at 3 or 6 months, meaning that the success rate was 97.3%. A meta-analysis of 3 of the 7 trials showed a pooled log odds ratio of 2.05 (95% CI: 1.19-2.91; p = 0.00), suggesting that recurrent bleeding was more likely to occur with observation or silver nitrate than with MWA.

The average pain level in a trial of 83 individuals was 1.83 during the MWA treatment and dropped to 0.95 an hour later. With minimal rates of rebleeding and complications, MWA is an all-around safe and efficient therapy for epistaxis.

Overall, an efficient and reasonably priced treatment option for the common ailment of epistaxis is microwave ablation. With a remarkably low risk of rebleeding for recurrent or idiopathic cases and little patient problems, this review demonstrates the effectiveness of MWA. Furthermore, the data indicates that MWA may be just as effective as or perhaps more successful than more conventional techniques like chemical cauterization or electrocautery. To learn more about the utility of MWA in treating epistaxis, more research is required, particularly randomized controlled studies.

Source:

Aziz, A. A., Shah, R., Aziz, M. A., Amir, M., & Ali, I. A. (2025). Gender-related differences in the hospitalization outcomes for Gastroparesis. Cureus, 17(6), e86239. https://doi.org/10.7759/cureus.86239