Vitamin D does not prevent postoperative Crohn's Disease after ileocolonic resection
Netherlands: Patients with Crohn's disease (CD) are generally known to be deficient in vitamin D and high-dose vitamin D is known to have anti-inflammatory effects in CD patients. However, according to a recent study administration of high-dose vitamin D did not prevent the postoperative occurrence of Crohn's disease after ileocolonic resection. The study is published in the journal Clinical Gastroenterology and Hepatology.
Jessica R. de Bruyn, University of Amsterdam, Amsterdam, the Netherlands, and colleagues conducted the study to determine whether high-dose vitamin D prevents postoperative recurrence of CD after ileocolonic resection.
For this study, CD patients undergoing ileocolonic resection were given weekly 25,000 IU oral vitamin D (n=72) or placebo (n=71) postoperatively. Patients were assessed at baseline and week 2, 6, 12, and 26 for laboratory and clinical parameters, and underwent ileocolonoscopy at 26 weeks. The primary endpoint was endoscopic recurrence on ileocolonoscopy at 26 weeks.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.