Oxycodone similar to acetaminophen and codeine combination in pain management
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Prescribing opioids for chronic pain has increased despite evidence of the association of their long-term use with adverse outcomes. A recent study found that oxycodone (strong opioid) did not provide superior pain relief compared with combination acetaminophen and codeine (mild opioid) after the first 7 days of fracture surgery, despite a 6-fold higher dose of opioid being delivered in the strong opioid group. The study findings were published in the journal JAMA Network Open on November 17, 2021.
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