Dual antiplatelet therapy equally effective in acute coronary syndrome
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The appropriate duration of dual antiplatelet therapy in patients at high risk for bleeding after the implantation of a drug-eluting coronary stent remains unclear. Valgimigli et al have shown that 1 month of dual antiplatelet therapy (DAPT) is noninferior to the continuation of therapy for at least 2 additional months with regard to the occurrence of net adverse clinical events and major adverse cardiac or cerebral events; along with the added advantage of lower incidence of major or clinically relevant nonmajor bleeding. The results of this multicenter, randomized, open-label, noninferiority trial with sequential superiority testing were published in the latest issue of NEJM last week.
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