Common bacteria may help some viruses that cause cancer by suppressing the Immune system
Written By : Isra Zaman
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-09-14 04:30 GMT | Update On 2022-09-14 12:02 GMT
Advertisement
Gut bacteria have a profound impact on health by aiding digestion, providing nutrients and metabolites, and working with the immune system to fend off pathogens. Some gut bacteria, however, have been implicated in progression of cancers of the gut and associated organs.
A new study by researchers from the University of Chicago shows that some commensal bacteria promote the development of leukemia caused by the murine leukemia virus (MuLV) by suppressing the animal's adaptive anti-tumor immune response. When both the virus and commensal bacteria are present in mice, three genes known as negative immune regulators are expressed more, or upregulated, which in turn tamps down the immune response that would otherwise kill the tumor cells. Two of these three negative immune regulators are also known to be indicators of poor prognosis for humans with some forms of cancer.
Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.