Gel like sieve in blood vessels helpful in repairing damaged hearts
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Drugs that repair damage to a gel-like layer in the tiny blood vessels of the heart could present a much-needed treatment for heart failure in people with diabetes, according to University of Bristol-led research funded by the British Heart Foundation and published in Diabetologia.
To see if repairing the glycocalyx improved the function of the heart, diabetic mice were given a substance known to restore the glycocalyx. These findings have far-reaching implications in protecting against other types of organ failure, since the glycocalyx is present in all blood vessels.
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