Journal Club - FAME 3 Subanalysis Adds Twist to Negative Primary Results
Ischemic heart disease is the leading cause of death globally. Coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI) are the two revascularization options for ischemic heart disease. However, the choice of the most appropriate revascularization modality is controversial and has been an issue of debate.
choice of revascularization and the status of percutaneous coronary intervention ie PCI in treating coronary artery disease. Previously in the FAME 2 trial the researchers concluded that in patients with stable coronary artery disease and functionally significant stenoses, FFR-guided PCI plus the best available medical therapy, as compared with the best available medical therapy alone, decreased the need for urgent revascularization. In patients without ischemia, the outcome appeared to be favorable with the best available medical therapy alone.
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